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AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas 鈥� immunology, oncology, neuroscience, and eye care 鈥� and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at听. Follow @abbvie on听,听,听,听,听听补苍诲听.
Envision spending your summer working with energetic colleagues and inspirational leaders, all while gaining world-class experience in one of the most dynamic organizations in the pharmaceutical industry. This is a reality for AbbVie Interns.听听
The Genomics Research Center (GRC) plays an integral role towards the goal of developing world class genetics and genomics research, focusing on finding the right targets and helping us better understand not only human disease biology but also the behavior of and response to our drugs in clinical trials. Within the GRC, the Human Genetics (HG) team assists in the identification and characterization of underlying genetic factors associated with diseases and aims to understand the mechanism of drug response through quantitative analyses. Major focuses include new target discovery via genetic evidence from population-based studies, large biobanks, molecular phenotypes, and deeper investigation of targets through functional genomics. This internship will focus on comparing and leveraging variant annotation tools (e.g., VEP, FAVOR, RegulomeDB, SpliceAI, AlphaGenome) and databases to annotate variants from real sequencing datasets, with the goal of prioritizing those most likely to have functional impact in association studies.听
Key responsibilities include:听
- Survey and compare major variant annotation tools (e.g., VEP, SnpEff, ANNOVAR).听
- Compare the gene and transcript lists of humans in RefSeq and Ensembl/GENCODE.听
- Explore and integrate multi-source annotations (e.g., ClinVar, HGMD, splice-disrupting variants in SpliceAI, functional scores in FAVOR, AlphaMissense & AlphaGenome, and regulatory features).听
- Annotate the variants in a WGS project using selected tools and support/conduct association analysis.听
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Minimum Qualifications听
- Currently enrolled in university, pursuing a PhD in Genome sciences, Bioinformatics, Biostatistics, Human genetics, Computer Science or other related fields听
- Must be enrolled in university for at least one semester following the internship听
- Expected graduation date between December 2026 鈥� July 2027听
- Proficient in programming languages (R or Python)听
- Strong written and verbal communication skills听
- Self-directed and able to work with minimal supervision听
Preferred Qualifications听
- Have experience performing variant annotation and prioritizing variants based on their annotations听
- Strong quantitative and analytical skills听
- Energetic and eager to tackle new projects and generate new ideas听
Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:听鈥�
The compensation range described below is the range of possible base pay compensation that the Company believes in听good faith it will pay for this role at the timeof this posting based on the job grade for this position. Individual听compensation paid within this range will depend on many factors including geographic location, andwe may ultimately听pay more or less than the posted range. This range may be modified in the future.鈥�
Benefits and Amenities听听
- Competitive pay听
- Relocation support for eligible students听
- Select wellness benefits and paid holiday / sick time
Note: No amount of pay听is considered to be听wages or compensation until such amount is earned, vested, and determinable.听The amount and availability of any bonus,commission, incentive, benefits, or any other form of compensation and benefits听that are allocable to a particular employee remains in the Company's sole and absolutediscretion unless and until paid and听may be modified at the Company鈥檚 sole and absolute discretion, consistent with applicable law.听
AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.鈥� Equal Opportunity Employer/Veterans/Disabled.听
US & Puerto Rico only - to learn more, visit听
US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:
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